PDB ID: 4FCD
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Structure summary
Code : | 4FCD PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Hydrolase/Hydrolase inhibitor | ||||||||||||
Title : | Potent and Selective Phosphodiesterase 10A Inhibitors | ||||||||||||
Release Data : | 2012-09-05 | ||||||||||||
Compound : |
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Source : |
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Authors : | Parris, K.D. | ||||||||||||
Keywords : | Binding Sites, Cyclic AMP, Cyclic GMP, Humans, Hydrolysis, Ligands, Phosphodiesterase Inhibitors, Phosphoric Diester Hydrolases, Recombinant Proteins, Structure-Activity Relationship, Hydrolase-Hydrolase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.020 Å ) | ||||||||||||
Citation : |
Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
Malamas, M.S.,Stange, H.,Schindler, R.
et al.
PubMed: 22902656 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | Q9Y233 (PDE10_HUMAN) | ||||||||||||||||
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