PDB ID: 4F64
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0S8 | 5-bromo-N~4~-[3-(3-methoxypropyl)-1h-pyrazol-5-yl]-N~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 4F64
Structure summary
Code : | 4F64 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex with compound 6 | ||||||||||||
Release Data : | 2012-06-06 | ||||||||||||
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Authors : | Norman, R.A., Breed, J., Ogg, D. | ||||||||||||
Keywords : | kinase, ATP binding, phosphorylation, trans-membrane, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.05 Å ) | ||||||||||||
Citation : |
Protein-Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase.
Norman, R.A.,Schott, A.K.,Andrews, D.M.
et al.
PubMed: 22612866 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P11362 (FGFR1_HUMAN) | ||||||||
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