Het-PDB Navi2 (PDB: 4F0X)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
0OR	N~3~-[(2r)-2-hydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-3,3-dimethylbutanoyl]-beta-alaninamide				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4F0X

Code :

4F0X PDBj RCSB PDB PDBe

Header :

LYASE

Title :

Crystal structure of human Malonyl-CoA Decarboxylase (Peroxisomal Isoform)

Release Data :

2013-03-20

Compound :

mol_id	molecule	chains	synonym
1	Malonyl-CoA decarboxylase, mitochondrial	A,B,C,D,E,F,G,H	MCD
	ec: 4.1.1.9

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: DCYLM, MLYCD expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET-DEST-42-112

Authors :

Aparicio, D., Perez, R., Fita, I.

Keywords :

Enzyme, Peroxisome, LYASE

Exp. method :

X-RAY DIFFRACTION ( 3.29 Å )

Citation :

Structural Asymmetry and Disulfide Bridges among Subunits Modulate the Activity of Human Malonyl-CoA Decarboxylase.

Aparicio, D.,Perez-Luque, R.,Carpena, X. et al.
(2013) J.Biol.Chem. 288 : 11907 - 11919

Chain :

A, B, C, D, E, F, G, H

UniProt :

O95822 (DCMC_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
H(+) + malonyl-CoA = acetyl-CoA + CO2	4.1.1.9	PubMed:10417274, PubMed:10455107, PubMed:15003260, PubMed:23482565, PubMed:9869665
H(+) + malonyl-CoA = acetyl-CoA + CO2	left-to-right	PubMed:23482565

PDB ID: 4F0X