PDB ID: 4EO8
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Structure summary
Code : | 4EO8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres | ||||||||||||
Release Data : | 2012-06-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Appleby, T.C., Canales, E., Watkins, W.J. | ||||||||||||
Keywords : | HCV, NS5B, RNA, RNA polymerase, polymerase inhibitor, Thumb Site 2 inhibitor, RNA-Dependent RNA Polymerase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.7980 Å ) | ||||||||||||
Citation : |
Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors.
Canales, E.,Carlson, J.S.,Appleby, T.
et al.
PubMed: 22664130 |
Reaction
Chain : | A, B | ||||||||||||||||||||
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UniProt : | P26663 (POLG_HCVBK) | ||||||||||||||||||||
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