Brand  (β version)

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Modified Residues
Code Name Link
C6G 6-(carboxymethoxy)-9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9h-purin-2-amine
Code : 4ENN
Header : DNA BINDING PROTEIN/DNA
Title : Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-carboxymethylguanine
Release Data : 2012-06-20
Compound :
mol_id molecule chains
1 Alkyltransferase-like protein 1 A,B
mol_id molecule chains
2 RNA (5'-R(*GP*CP*CP*AP*TP*GP*(C6G)P*CP*TP*AP*GP*TP*A)-3') C,D,E,F
Source :
mol_id organism_scientific organism_common expression_system
1 Schizosaccharomyces pombe 972h-  (taxid:284812) Fission yeast Escherichia coli  (taxid:562)
strain: 972 / ATCC 24843
gene: atl1, SPAC1250.04c
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Tubbs, J.L., Arvai, A.S., Tainer, J.A.
Keywords : Alkyltransferase, DNA repair, nucleotide excision repair, NER, base repair, DNA, DNA Damage, Guanine, Alkylation, DNA BINDING PROTEIN-DNA complex
Exp. method : X-RAY DIFFRACTION ( 2.8448 Å )
Citation :

Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.

Latypov, V.F.,Tubbs, J.L.,Watson, A.J.  et al.
(2012)  Mol.Cell  47 : 50 - 60

PubMed: 22658721
DOI: 10.1016/j.molcel.2012.04.028

Chain : A, B
UniProt : Q9UTN9 (ATL1_SCHPO)
Reaction : -