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Ligands
Code Name Style Show Link
CL Chloride ion
D5M 2'-deoxyadenosine-5'-monophosphate
DMS Dimethyl sulfoxide
EDO 1,2-ethanediol
Non-standard Residues
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Glycosylation
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Code : 4EK2   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : The structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to deoxyadenosine monophosphate
Release Data : 2012-05-09
Compound :
mol_id molecule chains synonym
1 Nucleoside diphosphate kinase A,B NDK, NDP kinase, Nucleoside-2-P kinase
ec: 2.7.4.6
Source :
mol_id organism_scientific expression_system
1 Burkholderia thailandensis  (taxid:271848) Escherichia coli  (taxid:562)
strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301
gene: ndk, BTH_I2231
Authors : Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Keywords : Seattle Structural Genomics Center for Infectious Disease, SSGCID, dAMP, NIAID, National Institute of Allergy and Infectious Diseases, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.000 Å )
Citation :

Combining functional and structural genomics to sample the essential Burkholderia structome.

Baugh, L.,Gallagher, L.A.,Patrapuvich, R.  et al.
(2013)  Plos One  8 : e53851 - e53851

PubMed: 23382856
DOI: 10.1371/journal.pone.0053851

Chain : A, B
UniProt : Q2SWE7 (NDK_BURTA)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'- deoxyribonucleoside 5'-triphosphate + ADP 2.7.4.6 HAMAP-Rule:MF_00451
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a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'- triphosphate + ADP 2.7.4.6 HAMAP-Rule:MF_00451
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Cofactor: Evidence: Note:
Mg(2+) ECO:0000255 | HAMAP-Rule:MF_00451
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