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Ligands
Code Name Style Show Link
FLC Citrate anion
CIS (15z)-N-((1s,2r,3e)-2-hydroxy-1-{[(3-O-sulfo-beta-D-galactopyranosyl)oxy]methyl}heptadec-3-enyl)tetracos-15-enamide
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
Modification
Code Name Show
Code : 4EI5   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1
Release Data : 2012-07-25
Compound :
mol_id molecule chains synonym
1 Antigen-presenting glycoprotein CD1d1 A,E CD1d
fragment: UNP residues 19-297
mol_id molecule chains
2 Beta-2-microglobulin B,F
fragment: UNP residues 21-119
mol_id molecule chains
3 Valpha1 XV19 Type II Natural Killer T cell receptor (mouse variable domain, human constant domain) C,G
fragment: extracellular domain (SEE REMARK 999)
mol_id molecule chains
4 Vbeta16 XV19 Type II Natural Killer T cell receptor (mouse variable domain, human constant domain) D,H
fragment: extracellular domain (SEE REMARK 999)
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Trichoplusia ni  (taxid:7111)
gene: Cd1d1, Cd1.1
expression_system_vector_type: baculovirus
expression_system_plasmid: pFasBacpHp10
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse Trichoplusia ni  (taxid:7111)
gene: B2m
expression_system_vector_type: baculovirus
expression_system_plasmid: pFasBacpHp10
mol_id organism_scientific organism_common expression_system
3 Mus musculus, Homo sapiens  (taxid:10090, 9606) Mouse, human Escherichia coli  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET30
mol_id organism_scientific organism_common expression_system
4 Mus musculus, Homo sapiens  (taxid:10090, 9606) Mouse, human Escherichia coli  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET30
Authors : Patel, O., Gras, S., Rossjohn, J.
Keywords : sulfatide, lipid, CD1d, NKT typeII, TCR, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 3.1000 Å )
Citation :

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor.

Patel, O.,Pellicci, D.G.,Gras, S.  et al.
(2012)  Nat.Immunol.  13 : 857 - 863

PubMed: 22820603
DOI: 10.1038/ni.2372

Chain : A, E
UniProt : P11609 (CD1D1_MOUSE)
Reaction : -
Chain : B, F
UniProt : P01887 (B2MG_MOUSE)
Reaction : -