Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
0OY (4-hydroxyphenyl)(morpholin-4-yl)methanone
MG Magnesium ion
Code : 4EGH   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Hsp90-alpha ATPase domain in complex with (4-Hydroxyphenyl)morpholin-4-yl methanone
Release Data : 2012-05-23
Compound :
mol_id molecule chains synonym
1 Heat shock protein HSP 90-alpha A Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38
fragment: N-terminal domain, residues 9-236
other_details: N-terminal domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
gene: HSP90AA1, HSP90A, HSPC1, HSPCA
expression_system_strain: BL21-DE3
expression_system_plasmid: pET-28a
Authors : Chen, W.J., Wood, S.P.
Keywords : Bergerat Fold, Hydrolase, ATP binding, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Fragment screening using capillary electrophoresis (CEfrag) for hit identification of heat shock protein 90 ATPase inhibitors.

Austin, C.,Pettit, S.N.,Magnolo, S.K.  et al.
(2012)  J Biomol Screen  17 : 868 - 876

PubMed: 22573733
DOI: 10.1177/1087057112445785

Chain : A
UniProt : P07900 (HS90A_HUMAN)
Reaction : -