PDB ID: 4EGA
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Structure summary
Code : | 4EGA PDBj RCSB PDB PDBe | ||||||||||||
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Header : | LIGASE/LIGASE INHIBITOR | ||||||||||||
Title : | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1320 | ||||||||||||
Release Data : | 2012-09-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J. | ||||||||||||
Keywords : | aminoacyl-tRNA synthetase, aaRS, MetRS, parasite, ligase, protein-inhibitor complex, Rossmann-fold, translation, nucleotide binding, Rossmann Fold, tRNA binding, ATP binding, LIGASE-LIGASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.698 Å ) | ||||||||||||
Citation : |
Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Koh, C.Y.,Kim, J.E.,Shibata, S.
et al.
PubMed: 22902861 |
Reaction
Chain : | A, B |
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UniProt : | Q38C91 (Q38C91_TRYB2) |
Reaction : | - |