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Ligands
Code Name Style Show Link
0OV [4-amino-2-{[(1s,2r)-2-methylcyclohexyl]oxy}-5-oxopyrido[2,3-D]pyrimidin-8(5h)-yl]acetonitrile
NMN Beta-nicotinamide ribose monophosphate
SO4 Sulfate ion
Non-standard Residues
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Glycosylation
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Code : 4EFE   PDBj   RCSB PDB   PDBe
Header : ligase/ligase inhibitor
Title : crystal structure of DNA ligase
Release Data : 2013-04-03
Compound :
mol_id molecule chains synonym
1 DNA ligase A Polydeoxyribonucleotide synthase [NAD(+)]
ec: 6.5.1.2
Source :
mol_id organism_scientific
1 Enterococcus faecalis  (taxid:1351)
Authors : Wei, Y., Wang, T., Charifson, P., Xu, W.
Keywords : DNA ligase, alpha-beta protein, adenylation, ligase-ligase inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

crystal structure of DNA ligase

Wang, T.,Xu, W.,Charifson, P.  et al.
To be Published 

Chain : A
UniProt : Q837V6 (DNLJ_ENTFA)
Reaction: EC: Evidence:
Physiological Direction:
NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho- (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta- nicotinamide D-nucleotide. 6.5.1.2 HAMAP- Rule:MF_01588
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