Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
0OW 4-amino-2-(cyclopentyloxy)-6-{[(1r,2s)-2-hydroxycyclopentyl]oxy}pyrimidine-5-carboxamide
NMN Beta-nicotinamide ribose monophosphate
SO4 Sulfate ion
Code : 4EFB
Header : ligase/ligase inhibitor
Title : Crystal structure of DNA ligase
Release Data : 2013-04-03
Compound :
mol_id molecule chains synonym
1 DNA ligase A Polydeoxyribonucleotide synthase [NAD(+)]
ec: 6.5.1.2
Source :
mol_id organism_scientific
1 Enterococcus faecalis  (taxid:1351)
synthetic: yes
other_details: This sequence occurs naturally in bacterial
Authors : Wei, Y., Wang, T., Charifson, P., Xu, W.
Keywords : alpha-beta protein, enzyme, adenylation, ligase-ligase inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.2 Å )
Citation :

Crystal structure of DNA ligase

Wang, T.,Charifson, P.,Xu, W.  et al.
To be Published 

Chain : A
UniProt : Q837V6 (DNLJ_ENTFA)
Reaction : NAD(+) + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + beta-nicotinamide D-nucleotide.