Het-PDB Navi2 (PDB: 4DX5)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
C14	Tetradecane	PoSSuM
D10	Decane	PoSSuM
D12	Dodecane	PoSSuM
DD9	Nonane	PoSSuM
GOL	Glycerol	PoSSuM
HEX	Hexane	PoSSuM
MIY	(4s,4as,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- carboxamide	PoSSuM
OCT	N-octane	PoSSuM
SO4	Sulfate ion	PoSSuM
UND	Undecane	PoSSuM
LMT	Dodecyl-beta-D-maltoside	PoSSuM
LMU	Dodecyl-alpha-D-maltoside	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4DX5

Code :

4DX5 PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN, TRANSPORT PROTEIN

Title :

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Release Data :

2012-05-02

Compound :

mol_id	molecule	chains
1	Acriflavine resistance protein B	A,B,C

mol_id	molecule	chains
2	DARPIN	D,E

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:83333)	Escherichia coli (taxid:562)
	strain: K12 gene: acrB, acrE, b0462, JW0451 expression_system_strain: C43(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET24

mol_id	organism_scientific	organism_common	expression_system
2	SYNTHETIC CONSTRUCT (taxid:32630)	ARTIFICIAL GENE	Escherichia coli (taxid:562)
	expression_system_strain: Xl1blue expression_system_vector_type: plasmid expression_system_plasmid: PQE30

Authors :

Eicher, T., Cha, H., Seeger, M.A., Brandstaetter, L., El-Delik, J., Bohnert, J.A., Kern, W.V., Verrey, F., Gruetter, M.G., Diederichs, K., Pos, K.M.

Keywords :

DARPin, multidrug efflux protein, MEMBRANE PROTEIN, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.900 Å )

Citation :

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.

Eicher, T.,Cha, H.J.,Seeger, M.A. et al.
(2012) Proc.Natl.Acad.Sci.USA 109 : 5687 - 5692

PDB ID: 4DX5