Het-PDB Navi2 (PDB: 4DX0)

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Ligands
Code	Name		Style	Show	Link
0MT	4-[(4r)-4-(4-nitrophenyl)-6-oxidanylidene-3-phenyl-1,4-dihydropyrrolo[3,4-C]pyrazol-5-yl]benzoic acid				PoSSuM

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Download interaction data: 4DX0

Code :

4DX0 PDBj RCSB PDB PDBe

Header :

PROTEIN BINDING/Hydrolase

Title :

Structure of the 14-3-3/PMA2 complex stabilized by a pyrazole derivative

Release Data :

2012-05-30

Compound :

mol_id	molecule	chains
1	14-3-3-like protein E	A
	fragment: UNP residues 1-238

mol_id	molecule	chains
2	N.plumbaginifolia H+-translocating ATPase mRNA	P
	ec: 3.6.3.6 fragment: UNP residues 926-956 mutation: T955D, V956I

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Nicotiana tabacum (taxid:4097)	American tobacco,tobacco	Escherichia coli (taxid:562)

mol_id	organism_scientific	organism_common	expression_system
2	Nicotiana plumbaginifolia (taxid:4092)	Leadwort-leaved tobacco	Escherichia coli (taxid:562)

Authors :

Richter, A., Rose, R., Hedberg, C., Waldmann, H., Ottmann, C.

Keywords :

14-3-3 fold, Pyrrolidinones, PROTEIN BINDING-Hydrolase complex

Exp. method :

X-RAY DIFFRACTION ( 3.4000 Å )

Citation :

An Optimised Small-Molecule Stabiliser of the 14-3-3-PMA2 Protein-Protein Interaction.

Richter, A.,Rose, R.,Hedberg, C. et al.
(2012) Chemistry 18 : 6520 - 6527

Chain :

UniProt :

Q42932 (Q42932_NICPL)

PDB ID: 4DX0