Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
FE Fe (III) ion
ZN Zinc ion
0LO 5-phenylpyridine-3-carboxylic acid
ACT Acetate ion
EDO 1,2-ethanediol
FUC Alpha-L-fucose
GOL Glycerol
NAG N-acetyl-D-glucosamine
SO4 Sulfate ion
Code : 4DSY
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC24201
Release Data : 2012-09-19
Compound :
mol_id molecule chains
1 Purple acid phosphatase A,B,C,D
ec: 3.1.3.2
fragment: unp residues 34-459
Source :
mol_id organism_scientific organism_common
1 Phaseolus vulgaris  (taxid:3885) French bean,kidney bean,string bean
gene: pap
Authors : Feder, D., Hussein, W.M., Clayton, D.J., Kan, M., Schenk, G., McGeary, R.P., Guddat, L.W.
Keywords : phosphatase, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.300 Å )
Citation :

Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.

Feder, D.,Hussein, W.M.,Clayton, D.J.  et al.
(2012)  Chem.Biol.Drug Des.  80 : 665 - 674

PubMed: 22943065
DOI: 10.1111/cbdd.12001

Chain : A, B, C, D
UniProt : O24319 (PPAF_PHAVU)
Reaction : A phosphate monoester + H(2)O = an alcohol + phosphate.