Het-PDB Navi2 (PDB: 4DPW)

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Ligands
Code	Name	Link
AGS	Phosphothiophosphoric acid-adenylate ester	PoSSuM
DP6	(3r)-3-hydroxy-5-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}-3-methylpentanoic acid	PoSSuM
FMT	Formic acid	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4DPW

Code :

4DPW PDBj RCSB PDB PDBe

Header :

LYASE

Title :

Crystal structure of Staphylococcus epidermidis D283A mevalonate diphosphate decarboxylase complexed with mevalonate diphosphate and ATPgS

Release Data :

2012-07-11

Compound :

mol_id	molecule	chains
1	Mevalonate diphosphate decarboxylase	A,B,C,D,E,F,G,H
	ec: 4.1.1.33 mutation: D283A

Source :

mol_id	organism_scientific	expression_system
1	Staphylococcus epidermidis (taxid:1282)	Escherichia coli (taxid:469008)
	gene: mvaD expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pT7HMT

Authors :

Barta, M.L., McWhorter, W.J., Geisbrecht, B.V.

Keywords :

GHMP Kinase Family, LYASE

Exp. method :

X-RAY DIFFRACTION ( 2.605 Å )

Citation :

Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase.

Barta, M.L.,McWhorter, W.J.,Miziorko, H.M. et al.
(2012) Biochemistry 51 : 5611 - 5621

PDB ID: 4DPW