PDB ID: 4DJX
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 4DJX PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Structure of BACE Bound to 5-(3-(5-chloropyridin-3-yl)phenyl)-5-cyclopropyl-2-imino-3-methylimidazolidin-4-one | ||||||||||||
Release Data : | 2012-03-21 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Strickland, C., Cumming, J. | ||||||||||||
Keywords : | BACE1, Alzheimers, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5000 Å ) | ||||||||||||
Citation : |
Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor.
Cumming, J.N.,Smith, E.M.,Wang, L.
et al.
PubMed: 22390835 |
Reaction
Chain : | A, B | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P56817 (BACE1_HUMAN) | ||||||||
|