PDB ID: 4DFL
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0K0 | 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-N-(piperidin-4-ylmethyl)pyrazine-2-carboxamide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 4DFL
Structure summary
Code : | 4DFL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine piperidine inhibitor | ||||||||||||
Release Data : | 2012-04-25 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lopez, M., Segarra, V., Vidal, B., Wenzkowski, C., Jestel, A., Krapp, S., Blaesse, M., Nagel, S., Schreiner, P. | ||||||||||||
Keywords : | SYK, TRANSFERASE, KINASE, INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.98 Å ) | ||||||||||||
Citation : |
Pyrazine-based Syk kinase inhibitors.
Forns, P.,Esteve, C.,Taboada, L.
et al.
PubMed: 22425453 |
Reaction
Chain : | A | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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