Brand  (β version)

PDB ID: 4DAJ

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
0HK (1r,2r,4s,5s,7s)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4DAJ   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN, Hydrolase
Title : Structure of the M3 Muscarinic Acetylcholine Receptor
Release Data : 2012-02-22
Compound :
mol_id molecule chains synonym
1 Muscarinic acetylcholine receptor M3, Lysozyme A,B,C,D Endolysin, Lysis protein, Muramidase
ec: 3.2.1.17
fragment: P08483 residues 57-259, 482-589, P00720 residues 1-161
mutation: C1054T, C1097A
other_details: Chimeric Protein
Source :
mol_id organism_scientific organism_common expression_system
1 Enterobacteria phage T4  (taxid:10665) Brown rat,rat,rats Spodoptera frugiperda  (taxid:7108)
gene: Chrm-3, Chrm3, E
expression_system_strain: Sf9
expression_system_plasmid: PVL1392
Authors : Kruse, A.C., Hu, J., Pan, A.C., Arlow, D.H., Rosenbaum, D.M., Rosemond, E., Green, H.F., Liu, T., Chae, P.S., Dror, R.O., Shaw, D.E., Weis, W.I., Wess, J., Kobilka, B.
Keywords : G protein-coupled receptor, muscarinic receptor, Acetylcholine receptor, SIGNALING PROTEIN, Hydrolase
Exp. method : X-RAY DIFFRACTION ( 3.40 Å )
Citation :

Structure and dynamics of the M3 muscarinic acetylcholine receptor.

Kruse, A.C.,Hu, J.,Pan, A.C.  et al.
(2012)  Nature  482 : 552 - 556

PubMed: 22358844
DOI: 10.1038/nature10867

Reaction

Chain : A, B, C, D
UniProt : P08483 (ACM3_RAT)
Reaction : -
Chain : A, B, C, D
UniProt : P00720 (ENLYS_BPT4)
Reaction: EC: Evidence:
Physiological Direction:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. 3.2.1.17 HAMAP-Rule:MF_04110, PubMed:4865643
-