Het-PDB Navi2 (PDB: 4D8S)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CA	Calcium ion				PoSSuM
0HX	Pentan-3-yl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4D8S

Code :

4D8S PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Influenza NA in complex with antiviral compound

Release Data :

2013-02-13

Compound :

mol_id	molecule	chains
1	Neuraminidase	A
	ec: 3.2.1.18 mutation: G293N

Source :

mol_id	organism_scientific
1	Influenza A virus (taxid:385580)
	strain: A/DUCK/UKRAINE/1/1963 H3N8

Authors :

Kerry, P.S., Russell, R.J.M.R.

Keywords :

Hydrolase, Neuraminidase

Exp. method :

X-RAY DIFFRACTION ( 2.398 Å )

Citation :

Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.

Bhatt, B.,Bohm, R.,Kerry, P.S. et al.
(2012) J.Med.Chem. 55 : 8963 - 8968

Chain :

UniProt :

Q07599 (NRAM_I63A3)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha- (2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.	3.2.1.18	HAMAP- Rule:MF_04071
	-	HAMAP- Rule:MF_04071

PDB ID: 4D8S