Brand  (β version)

PDB ID: 4D46

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Ligands
Code Name Style Show Link
J47 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 4D46   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of E. coli FabI in complex with NAD and 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile
Release Data : 2015-03-04
Compound :
mol_id molecule chains synonym
1 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] A,B ENOYL-ACP REDUCTASE
ec: 1.3.1.9
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:469008) ESCHERICHIA COLI  (taxid:469008)
strain: BL21(DE3)
expression_system_strain: BL21(DE3)
expression_system_plasmid: PET23B
Authors : Tareilus, M., Schiebel, J., Chang, A., Tonge, P.J., Sotriffer, C.A., Kisker, C.
Keywords : ENOYL-ACP REDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE SUPERFAMILY, ESCHERICHIA COLI, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, ECFABI, FABI, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction.

Schiebel, J.,Chang, A.,Merget, B.  et al.
(2015)  Biochemistry  54 : 1943

PubMed: 25706582
DOI: 10.1021/BI5014358

Reaction

Chain : A, B
UniProt : C6EFU4
Reaction : -