Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
IUP 5-(hydro)peroxoisourate
MPD (4s)-2-methyl-2,4-pentanediol
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 4D13   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 2.2 kGy)
Release Data : 2014-10-29
Compound :
mol_id molecule chains synonym
1 URICASE A URATE OXIDASE
ec: 1.7.3.3
Source :
mol_id organism_scientific expression_system
1 ASPERGILLUS FLAVUS  (taxid:5059) ESCHERICHIA COLI  (taxid:562)
Authors : Bui, S., Steiner, R.A.
Keywords : OXIDOREDUCTASE, COFACTOR-FREE OXIDASE
Exp. method : X-RAY DIFFRACTION ( 1.30 Å )
Citation :

Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.

Bui, S.,von Stetten, D.,Jambrina, P.G.  et al.
(2014)  Angew. Chem. Int. Ed. Engl.  53 : 13710 - 13714

PubMed: 25314114
DOI: 10.1002/anie.201405485

Chain : A
UniProt : Q00511 (URIC_ASPFL)
Reaction: EC: Evidence:
Physiological Direction:
H2O + O2 + urate = 5-hydroxyisourate + H2O2 1.7.3.3 PubMed:1339455, PubMed:17020862, PubMed:25314114, Ref.3
left-to-right PubMed:1339455, PubMed:17020862, Ref.3