Het-PDB Navi2 (PDB: 4CWA)

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Ligands
Code	Name		Style	Show	Link
JA2	5-(1h-benzimidazol-2-yl)pentan-1-amine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4CWA

Code :

4CWA PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 1H-Benzimidazole-2-pentanamine

Release Data :

2014-10-08

Compound :

mol_id	molecule	chains
1	SPERMIDINE SYNTHASE	A,B,C
	ec: 2.5.1.16 fragment: RESIDUES 40-321

Source :

mol_id	organism_scientific	expression_system
1	PLASMODIUM FALCIPARUM (taxid:36329)	ESCHERICHIA COLI (taxid:469008)
	strain: 3D7 expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: P15-TEV-LIC

Authors :

Sprenger, J., Halander, J.C., Svensson, B., Al-Karadaghi, S., Persson, L.

Keywords :

TRANSFERASE, AMINOPROPYL TRANSFERASE, POLYAMINE PATHWAY, ROSSMANN-LIKE FOLD

Exp. method :

X-RAY DIFFRACTION ( 2.02 Å )

Citation :

Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design.

Sprenger, J.,Svensson, B.,Halander, J. et al.
(2015) Acta Crystallogr.,Sect.D 71 : 484

PDB ID: 4CWA