Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
3PH 1,2-diacyl-glycerol-3-sn-phosphate
DAO Lauric acid
DPO Diphosphate
FTT 3-hydroxy-tetradecanoic acid
GCS D-glucosamine
GMH L-glycero-D-manno-heptopyranose
KDO 3-deoxy-D-manno-oct-2-ulosonic acid
LDA Lauryl dimethylamine-N-oxide
MYR Myristic acid
PA1 2-amino-2-deoxy-alpha-D-glucopyranose
PO4 Phosphate ion
Code : 4CU4
Header : TRANSPORT PROTEIN/ANTIBIOTIC
Title : FhuA from E. coli in complex with the lasso peptide microcin J25 (MccJ25)
Release Data : 2014-04-09
Compound :
mol_id molecule chains synonym
1 FERRICHROME-IRON RECEPTOR A FHUA, FERRIC HYDROXAMATE RECEPTOR, FERRIC HYDROXAMATE UPTAKE
fragment: RESIDUES 53-747
other_details: HIS-TAG BETWEEN RESIDUE P405 AND V417. SEQUENCE INSERTED SSHHHHHHGSS
mol_id molecule chains synonym
2 MICROCIN J25 B MICROCIN MCCJ25, MCCJ25
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI STR. K-12 SUBSTR. MG1655  (taxid:511145) ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_variant: PLYSS
expression_system_vector_type: PLASMID
expression_system_plasmid: PET21A
mol_id organism_scientific
2 ESCHERICHIA COLI STR. K-12 SUBSTR. MC4100  (taxid:1403831)
Authors : Mathavan, I., Rebuffat, S., Beis, K.
Keywords : TRANSPORT PROTEIN-ANTIBIOTIC COMPLEX, LIPOPOLYSACCHARIDE, DETERGENT
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Structural Basis for Hijacking Siderophore Receptors by Antimicrobial Lasso Peptides.

Mathavan, I.,Zirah, S.,Mehmood, S.  et al.
(2014)  Nat.Chem.Biol.  10 : 340

PubMed: 24705590
DOI: 10.1038/NCHEMBIO.1499

Chain : A
UniProt : P06971 (FHUA_ECOLI)
Reaction : -
Chain : B
UniProt : Q9X2V7 (MCJA_ECOLX)
Reaction : -