Het-PDB Navi2 (PDB: 4CLD)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
ACT	Acetate ion	PoSSuM
JUO	2-amino-4-thiomorpholino-7h-pyrrolo[2,3-D]pyrimidine-5-carbonitrile	PoSSuM
NAP	Nadp nicotinamide-adenine-dinucleotide phosphate	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4CLD

Code :

4CLD PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor

Release Data :

2015-01-21

Compound :

mol_id	molecule	chains	synonym
1	PTERIDINE REDUCTASE 1	A,B,C,D	PTR1
	ec: 1.5.1.33

Source :

mol_id	organism_scientific	expression_system
1	TRYPANOSOMA BRUCEI BRUCEI (taxid:5702)	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PET15B

Authors :

Barrack, K.L., Hunter, W.N.

Keywords :

OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 1.77 Å )

Citation :

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1.

Khalaf, A.I.,Huggan, J.K.,Suckling, C.J. et al.
(2014) J.Med.Chem. 57 : 6479

PDB ID: 4CLD