Brand  (β version)

PDB ID: 4C3O

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Ligands
Code Name Style Show Link
NFU Formyl[bis(hydrocyanato-1kappac)]ironnickel(Fe-ni) PoSSuM
CL Chloride ion PoSSuM
MG Magnesium ion PoSSuM
F4S Fe4-s3 cluster PoSSuM
SF4 Iron/sulfur cluster PoSSuM
F3S Fe3-s4 cluster PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 4C3O   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Structure and function of an oxygen tolerant NiFe hydrogenase from Salmonella
Release Data : 2014-01-29
Compound :
mol_id molecule chains synonym
1 HYDROGENASE-1 LARGE SUBUNIT A,C,E OXYGEN TOLERANT NIFE HYDROGENASE
ec: 1.12.7.2
fragment: RESIDUES 1-585
mol_id molecule chains synonym
2 HYDROGENASE-1 SMALL SUBUNIT B,D,F OXYGEN TOLERANT NIFE HYDROGENASE
ec: 1.12.7.2
fragment: RESIDUES 46-314
Source :
mol_id organism_scientific expression_system
1 SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. LT2  (taxid:99287) SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM  (taxid:90371)
variant: LT2A
mol_id organism_scientific expression_system
2 SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. LT2  (taxid:99287) SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM  (taxid:90371)
variant: LT2A
Authors : Bowman, L., Flanagan, L., Fyfe, P.K., Parkin, A., Hunter, W.N., Sargent, F.
Keywords : OXIDOREDUCTASE, HYDROGEN METABOLISM, NIFE HYDROGENASE
Exp. method : X-RAY DIFFRACTION ( 3.20 Å )
Citation :

How the Structure of the Large Subunit Controls Function in an Oxygen-Tolerant [Nife]-Hydrogenase.

Bowman, L.,Flanagan, L.,Fyfe, P.K.  et al.
(2014)  Biochem.J.  458 : 449

PubMed: 24428762
DOI: 10.1042/BJ20131520

How Salmonella Oxidises H(2) Under Aerobic Conditions.

Parkin, A.,Bowman, L.,Roessler, M.M.  et al.
(2012)  FEBS Lett.  586 : 536

PubMed: 21827758
DOI: 10.1016/J.FEBSLET.2011.07.044

Reaction

Chain : A, C, E
UniProt : Q8ZPH0 (Q8ZPH0_SALTY)
Reaction: EC: Evidence:
Physiological Direction:
H2 + A = AH2 1.12.99.6 ARBA:ARBA00048757
-
Cofactor: Evidence: Note:
Fe cation ECO:0000256 | PIRSR:PIRSR601501-1
-
Ni(2+) ECO:0000256 | ARBA:ARBA00001967
ECO:0000256 | PIRSR:PIRSR601501-1
-
Chain : B, D, F
UniProt : Q8ZPG9 (Q8ZPG9_SALTY)
Reaction: EC: Evidence:
Physiological Direction:
H2 + A = AH2 1.12.99.6 ARBA:ARBA00048757
-
Cofactor: Evidence: Note:
[3Fe-4S] cluster ECO:0000256 | ARBA:ARBA00001927
-
[4Fe-4S] cluster ECO:0000256 | ARBA:ARBA00001966
-