Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
NA Sodium ion
0GJ L-alpha-glutamyl-N-{(1s)-4-{[amino(iminio)methyl]amino}-1-[(1s)-2-chloro-1-hydroxyethyl]butyl}glycinamide
GOL Glycerol
Code : 4BXW
Header : BLOOD CLOTTING
Title : Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis
Release Data : 2013-07-31
Compound :
mol_id molecule chains
1 FACTOR XA A,B
fragment: EGF2-CATALYTIC DOMAIN CONSTRUCT, RESIDUES 41-463
other_details: PSEUTARIN C CATALYTIC SUBUNIT
mol_id molecule chains synonym
2 COAGULATION FACTOR V F FACTOR V A2 PEPTIDE
fragment: A2 PEPTIDE, RESIDUES 693-710
other_details: 663 TO 680 OF P. TEXTILIS FV
Source :
mol_id organism_scientific organism_common expression_system
1 PSEUDONAJA TEXTILIS  (taxid:8673) AUSTRALIAN EASTERN BROWN SNAKE ESCHERICHIA COLI  (taxid:469008)
organ: VENOM GLAND
expression_system_strain: BL21(DE3)
expression_system_variant: STAR
expression_system_vector_type: PLASMID
expression_system_vector: PET23
mol_id organism_scientific
2 ESCHERICHIA COLI  (taxid:562)
synthetic: yes
Authors : Lechtenberg, B.C., Murray-Rust, T.A., Johnson, D.J.D., Adams, T.E., Krishnaswamy, S., Camire, R.M., Huntington, J.A.
Keywords : BLOOD CLOTTING, BLOOD COAGULATION, PROTHROMBINASE, FACTOR V, FACTOR X, HYDROLASE, PROTEASE
Exp. method : X-RAY DIFFRACTION ( 2.71 Å )
Citation :

Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis.

Lechtenberg, B.C.,Murray-Rust, T.A.,Johnson, D.J.  et al.
(2013)  Blood  122 : 2777

PubMed: 23869089
DOI: 10.1182/BLOOD-2013-06-511733

Chain : A, B
UniProt : Q6IT10 (No found in current UniProtKB/SwissProt)
Reaction : -
Chain : F
UniProt : Q593B6 (FA5_PSETE)
Reaction : -