Brand  (β version)

PDB ID: 4BVV

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CPF 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4BVV   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.
Release Data : 2014-07-16
Compound :
mol_id molecule chains synonym
1 APOLIPOPROTEIN(A) A APO(A), LP(A)
ec: 3.4.21.-
fragment: KRINGLE DOMAIN V, RESIDUES 4227-4307
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN KOMAGATAELLA PASTORIS  (taxid:4922)
expression_system_strain: X-33
expression_system_vector_type: PLASMID
expression_system_plasmid: PPICZALPHAC
Authors : Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
Keywords : HYDROLASE, CARDIOVASCULAR DISEASE, DRUG DISCOVERY, OPTICAL BIOSENSORS
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A)

Sandmark, J.,Althage, M.,Andersson, G.M.K.  et al.
To be Published 

Reaction

Chain : A
UniProt : P08519 (APOA_HUMAN)
Reaction : -