Het-PDB Navi2 (PDB: 4BUY)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
ZN	Zinc ion	PoSSuM
SO4	Sulfate ion	PoSSuM
F37	(5s)-5-methyl-5-[4-(4-oxidanylidene-3h-quinazolin-2-yl)phenyl]imidazolidine-2,4-dione	PoSSuM
GOL	Glycerol	PoSSuM
PEG	Di(hydroxyethyl)ether	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4BUY

Code :

4BUY PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of human tankyrase 2 in complex with 5-methyl-5-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)imidazolidine-2,4-dione

Release Data :

2013-10-30

Compound :

mol_id	molecule	chains	synonym
1	TANKYRASE-2	A,B	TANK2, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 6, ARTD 6, POLY ADP-RIBOSE POLYMERASE 5B, TNKS-2, TRF1-INTERACTING ANKYRIN-RELATED ADP-RIBOSE POLYMERASE 2, TANKYRASE II, TANKYRASE-LIKE PROTEIN, TANKYRASE-RELATED PROTEIN
	ec: 2.4.2.30 fragment: C-TERMINAL FRAGMENT, RESIDUES 946-1162

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_variant: ROSETTA 2 expression_system_vector_type: PLASMID expression_system_plasmid: PNIC28-BSA4

Authors :

Haikarainen, T., Narwal, M., Lehtio, L.

Keywords :

TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.90 Å )

Citation :

Para-Substituted 2-Phenyl-3,4-Dihydroquinazolin-4-Ones as Potent and Selective Tankyrase Inhibitors.

Haikarainen, T.,Koivunen, J.,Narwal, M. et al.
(2013) Chemmedchem 8 : 1978

PDB ID: 4BUY