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Ligands
Code Name Style Show Link
GOL Glycerol
JG7 (2s,4r)-4-[2-chloranyl-4-(4-ethylpiperazin-1-yl)phenyl]sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(trifluoromethyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide
Non-standard Residues
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Glycosylation
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Code : 4BS6   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : MOUSE CATHEPSIN S WITH COVALENT LIGAND
Release Data : 2014-06-18
Compound :
mol_id molecule chains
1 CATHEPSIN S A,B
ec: 3.4.22.27
fragment: RESIDUES 116-340
Source :
mol_id organism_scientific organism_common expression_system
1 MUS MUSCULUS  (taxid:10090) HOUSE MOUSE ESCHERICHIA COLI  (taxid:562)
Authors : Banner, D.W., Benz, J., Gsell, B., Stihle, M., Ruf, A., Haap, W.
Keywords : HYDROLASE, CYSTEINE PROTEASE, COVALENT LIGAND
Exp. method : X-RAY DIFFRACTION ( 1.20 Å )
Citation :

Cathepsin S Nitrile Inhibitors

Haap, W.,Banner, D.W.
To be Published 

Chain : A, B
UniProt : O70370 (CATS_MOUSE)
Reaction: EC: Evidence:
Physiological Direction:
Similar to cathepsin L, but with much less activity on Z-Phe- Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound. 3.4.22.27 -
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