Brand  (β version)

PDB ID: 4BQT

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Ligands
Code Name Style Show Link
C5E (1r,5s)-1,2,3,4,5,6-hexahydro-8h-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one PoSSuM
CL Chloride ion PoSSuM
CO Cobalt (II) ion PoSSuM
Non-standard Residues
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Structure summary

Code : 4BQT   PDBj   RCSB PDB   PDBe
Header : RECEPTOR
Title : Aplysia californica AChBP in complex with Cytisine
Release Data : 2013-06-12
Compound :
mol_id molecule chains synonym
1 SOLUBLE ACETYLCHOLINE RECEPTOR A,B,C,D,E ACETYLCHOLINE BINDING PROTEIN, ACHBP
fragment: RESIDUES 20-236
Source :
mol_id organism_scientific organism_common expression_system
1 APLYSIA CALIFORNICA  (taxid:6500) CALIFORNIA SEA HARE SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_cell_line: Sf21
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PFASTBAC
Authors : Rucktooa, P., Haseler, C.A., vanElke, R., Smit, A.B., Gallagher, T., Sixma, T.K.
Keywords : RECEPTOR
Exp. method : X-RAY DIFFRACTION ( 2.88 Å )
Citation :

Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors Through Study of Ligand Complexes with Acetylcholine-Binding Protein.

Rucktooa, P.,Haseler, C.A.,Van Elk, R.  et al.
(2012)  J.Biol.Chem.  287 : 23283

PubMed: 22553201
DOI: 10.1074/JBC.M112.360347

Reaction

Chain : A, B, C, D, E
UniProt : Q8WSF8 (Q8WSF8_APLCA)
Reaction : -