Brand  (β version)

PDB ID: 4BFQ

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Ligands
Code Name Style Show Link
083 4,6-dimethyl-N'-(3-pyridin-2-ylisoquinolin-1-yl)pyrimidine-2-carboximidamide PoSSuM
GOL Glycerol PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 4BFQ   PDBj   RCSB PDB   PDBe
Header : RECEPTOR
Title : Assembly of a triple pi-stack of ligands in the binding site of Aplysia californica acetylcholine binding protein (AChBP)
Release Data : 2013-05-22
Compound :
mol_id molecule chains synonym
1 SOLUBLE ACETYLCHOLINE RECEPTOR A,B,C,D,E ACETYLCHOLINE BINDING PROTEIN
Source :
mol_id organism_scientific organism_common expression_system
1 APLYSIA CALIFORNICA  (taxid:6500) CALIFORNIA SEA HARE SPODOPTERA FRUGIPERDA  (taxid:7108)
cell: GLIAL CELL
expression_system_common: FALL ARMYWORM
expression_system_cell_line: SF9
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PFASTBACI
Authors : Stornaiuolo, M., De Kloe, G.E., Rucktooa, P., Fish, A., van Elk, R., Edink, E.S., Bertrand, D., Smit, A.B., de Esch, I.J.P., Sixma, T.K.
Keywords : RECEPTOR, ACETYLCHOLINE BINDING PROTEIN, NICOTINIC ACETYLCHOLINE RECEPTOR, CYS-LOOP RECEPTOR, NACHR, ION CHANNEL, PI-STACKING, TRIPLE LIGAND BINDING, DRUG DESIGN
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

Assembly of a Pi-Pi Stack of Ligands in the Binding Site of an Acetylcholine Binding Protein

Stornaiuolo, M.,De Kloe, G.E.,Rucktooa, P.  et al.
(2013)  Nat.Commun.  4 : 1875

PubMed: 23695669
DOI: 10.1038/NCOMMS2900

Reaction

Chain : A, B, C, D, E
UniProt : Q8WSF8 (Q8WSF8_APLCA)
Reaction : -