Brand  (β version)

color scheme of protein:

hetatm:

chain:

Code Name Link
CL Chloride ion
HO Holmium atom
Code : 4BDW
Header : hydrolase
Title : the structure of the fni-egf tandem domain of coagulation factor xii in complex with holmium
Release Data : 2013-02-13
Compound :
mol_id 1
molecule coagulation factor xiia heavy chain
chain A
fragment fni-egf, residues 133-215
synonym coagulation factor xii, hageman factor, haf
ec 3.4.21.38
engineered yes
Source :
mol_id 1
organism_scientific Homo sapiens
organism_taxid 9606
expression_system Komagataella pastoris
expression_system_taxid 4922
expression_system_strain x-33
expression_system_vector_type plasmid
expression_system_plasmid ppiczalpha
Authors : D.X.Beringer, L.M.J.Kroon-Batenburg
Keywords : hydrolase, fni domain, egf domain
Exp. method : X-ray diffraction ( 2.5 Å )
Chain : A
UniProt : P00748 (FA12_HUMAN)
Reaction : Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.