Het-PDB Navi2 (PDB: 4BDW)

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Ligands
Code	Name		Style	Show	Link
CL	Chloride ion				PoSSuM
HO	Holmium atom				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4BDW

Code :

4BDW PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

The structure of the FnI-EGF tandem domain of coagulation factor XII in complex with Holmium

Release Data :

2013-02-13

Compound :

mol_id	molecule	chains	synonym
1	COAGULATION FACTOR XIIA HEAVY CHAIN	A	COAGULATION FACTOR XII, HAGEMAN FACTOR, HAF
	ec: 3.4.21.38 fragment: FNI-EGF, RESIDUES 133-215

Source :

mol_id	organism_scientific	expression_system
1	HOMO SAPIENS (taxid:9606)	KOMAGATAELLA PASTORIS (taxid:4922)
	expression_system_strain: X-33 expression_system_vector_type: PLASMID expression_system_plasmid: PPICZALPHA

Authors :

Beringer, D.X., Kroon-Batenburg, L.M.J.

Keywords :

HYDROLASE, FNI DOMAIN, EGF DOMAIN

Exp. method :

X-RAY DIFFRACTION ( 2.501 Å )

Citation :

The Structure of the Fni-Egf-Like Tandem Domain of Coagulation Factor Xii Solved Using Siras.

Beringer, D.X.,Kroon-Batenburg, L.M.J.
(2013) Acta Crystallogr.,Sect.F 69 : 94

Chain :

UniProt :

P00748 (FA12_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
Selective cleavage of Arg-\|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.	3.4.21.38	-
	-	-

PDB ID: 4BDW