Brand  (β version)

PDB ID: 4BDW

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
HO Holmium atom PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4BDW   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : The structure of the FnI-EGF tandem domain of coagulation factor XII in complex with Holmium
Release Data : 2013-02-13
Compound :
mol_id molecule chains synonym
1 COAGULATION FACTOR XIIA HEAVY CHAIN A COAGULATION FACTOR XII, HAGEMAN FACTOR, HAF
ec: 3.4.21.38
fragment: FNI-EGF, RESIDUES 133-215
Source :
mol_id organism_scientific expression_system
1 HOMO SAPIENS  (taxid:9606) KOMAGATAELLA PASTORIS  (taxid:4922)
expression_system_strain: X-33
expression_system_vector_type: PLASMID
expression_system_plasmid: PPICZALPHA
Authors : Beringer, D.X., Kroon-Batenburg, L.M.J.
Keywords : HYDROLASE, FNI DOMAIN, EGF DOMAIN
Exp. method : X-RAY DIFFRACTION ( 2.501 Å )
Citation :

The Structure of the Fni-Egf-Like Tandem Domain of Coagulation Factor Xii Solved Using Siras.

Beringer, D.X.,Kroon-Batenburg, L.M.J.
(2013)  Acta Crystallogr.,Sect.F  69 : 94

PubMed: 23385745
DOI: 10.1107/S1744309113000286

Reaction

Chain : A
UniProt : P00748 (FA12_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa. 3.4.21.38 PubMed:2019570, PubMed:8427954
-