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Ligands
Code Name Style Show Link
FVQ 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside
Non-standard Residues
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Glycosylation
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Code : 4AV4   PDBj   RCSB PDB   PDBe
Header : CELL ADHESION
Title : FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine
Release Data : 2012-06-27
Compound :
mol_id molecule chains
1 FIMH A
fragment: LECTIN DOMAIN, RESIDUES 10-167
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:364106) ESCHERICHIA COLI  (taxid:469008)
strain: UTI89
expression_system_strain: BL21(DE3)
expression_system_variant: C43
expression_system_vector_type: PLASMID
expression_system_vector: PET24A
Authors : Bouckaert, J., Touaibia, M., Roos, G., Shiao, T.C., Wang, Q., Papadopoulos, A., Roy, R.
Keywords : CELL ADHESION, FIMBRIAE, VARIABLE IMMUNOGLOBULIN FOLD, URINARY TRACT INFECTION
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.

Wellens, A.,Lahmann, M.,Touaibia, M.  et al.
(2012)  Biochemistry  51 : 4790

PubMed: 22657089
DOI: 10.1021/BI300251R

Chain : A
UniProt : A2IC68 (A2IC68_ECOLX)
Reaction : -