Het-PDB Navi2 (PDB: 4AMJ)

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Ligands
Code	Name	Link
CVD	(2s)-1-(8h-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol	PoSSuM
NA	Sodium ion	PoSSuM
2CV	Hega-10	PoSSuM

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Download interaction data: 4AMJ

Code :

4AMJ PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN

Title :

Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist carvedilol

Release Data :

2012-05-23

Compound :

mol_id	molecule	chains	synonym
1	BETA-1 ADRENERGIC RECEPTOR	A,B	BETA-1 ADRENORECEPTOR, BETA-1 ADRENOCEPTOR, BETA-T
	fragment: RESIDUES 33-243,272-368 mutation: YES

Source :

mol_id	organism_scientific	organism_common	expression_system
1	MELEAGRIS GALLOPAVO (taxid:9103)	TURKEY	TRICHOPLUSIA NI (taxid:7111)
	cell: ERYTHROCYTE expression_system_common: CABBAGE LOOPER expression_system_cell_line: High Five expression_system_vector_type: BACULOVIRUS expression_system_plasmid: PBACPAK8

Authors :

Warne, T., Edwards, P.C., Leslie, A.G., Tate, C.G.

Keywords :

MEMBRANE PROTEIN, 7TMR BETA1-ADRENOCEPTOR, STABILISING MUTATIONS, BIASED AGONIST

Exp. method :

X-RAY DIFFRACTION ( 2.30 Å )

Citation :

Crystal Structures of a Stabilized Beta1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol

Warne, T.,Edwards, P.C.,Leslie, A.G. et al.
(2012) Structure 20 : 841

PDB ID: 4AMJ