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Ligands
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IZN (4bs,6s)-6-methoxy-1,4,6,7,9,10,12,13-octahydro-3h,5h-pyrano[4',3':3,4]pyrido[2,1-I]indol-3-one
1PE Pentaethylene glycol
MG Magnesium ion
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Code : 4ALX   PDBj   RCSB PDB   PDBe
Header : ACETYLCHOLINE-BINDING PROTEIN
Title : Crystal Structure of Ls-AChBP complexed with the potent nAChR antagonist DHbE
Release Data : 2012-08-29
Compound :
mol_id molecule chains synonym
1 ACETYLCHOLINE BINDING PROTEIN A,B,C,D,E,F,G,H,I,J ACH-BINDING PROTEIN, ACHBP
Source :
mol_id organism_scientific organism_common expression_system
1 LYMNAEA STAGNALIS  (taxid:6523) GREAT POND SNAIL SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_strain: SF9
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PFASTBAC
Authors : Shahsavar, A., Kastrup, J.S., Nielsen, E.O., Kristensen, J.L., Gajhede, M., Balle, T.
Keywords : ACETYLCHOLINE-BINDING PROTEIN, LYMNAEA STAGNALIS, DIHYDRO-B-ERYTHROIDINE, ANTAGONIST, C-LOOP
Exp. method : X-RAY DIFFRACTION ( 2.300 Å )
Citation :

Crystal Structure of Lymnaea Stagnalis Achbp Complexed with the Potent Nachr Antagonist Dh-Betab-E Suggests a Unique Mode of Antagonism

Shahsavar, A.,Kastrup, J.S.,Nielsen, E.O.  et al.
(2012)  Plos One  7 : 40757

PubMed: 22927902
DOI: 10.1371/JOURNAL.PONE.0040757

Chain : A, B, C, D, E, F, G, H, I, J
UniProt : P58154 (ACHP_LYMST)
Reaction : -