PDB ID: 4A50
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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ADP | Adenosine-5'-diphosphate | PoSSuM | |||
DQ6 | (2s)-2-amino-5-(3-methylphenyl)-5,5-diphenylpropanoic acid | PoSSuM | |||
DQ7 | (2r)-2-amino-5-(3-methylphenyl)-5,5-diphenylpropanoic acid | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 4A50
Structure summary
Code : | 4A50 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | CELL CYCLE | ||||||||||||
Title : | Crystal structure of human kinesin Eg5 in complex with 2-Amino-5-(3-methylphenyl)-5,5-diphenylpentanoic acid | ||||||||||||
Release Data : | 2012-10-31 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kaan, H.Y.K., Kozielski, F. | ||||||||||||
Keywords : | CELL CYCLE, MITOSIS, INHIBITOR, KSP | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.75 Å ) | ||||||||||||
Citation : |
Triphenylbutanamines: Kinesin Spindle Protein Inhibitors with in Vivo Antitumor Activity.
Wang, F.,Good, J.A.D.,Rath, O.
et al.
PubMed: 22248262 |
Reaction
Chain : | A |
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UniProt : | P52732 (KIF11_HUMAN) |
Reaction : | - |