Brand  (β version)

PDB ID: 4A1U

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
B3A (3s)-3-aminobutanoic acid
B3E (3s)-3-aminohexanedioic acid
HR7 (3s)-3-amino-6-[(diaminomethylidene)amino]hexanoic acid
HT7 (3s)-3-amino-4-(1h-indol-3-yl)butanoic acid
Glycosylation
Code Name Emphasize
Modification
Code Name Show
ACE Acetyl group
NH2 Amino group

Structure summary

Code : 4A1U   PDBj   RCSB PDB   PDBe
Header : APOPTOSIS
Title : Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL
Release Data : 2011-12-28
Compound :
mol_id molecule chains synonym
1 BCL-2-LIKE PROTEIN 1 A BCL-XL, BCL2-L-1, APOPTOSIS REGULATOR BCL-X
fragment: RESIDUES 1-26,83-209
mol_id molecule chains
2 ALPHA-BETA-FOLDAMER 2C B
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_vector: PGEX
mol_id organism_scientific
2 SYNTHETIC CONSTRUCT  (taxid:32630)
synthetic: yes
Authors : Boersma, M.D., Haase, H.S., Kaufman, K.J., Horne, W.S., Lee, E.F., Clarke, O.B., Smith, B.J., Colman, P.M., Gellman, S.H., Fairlie, W.D.
Keywords : APOPTOSIS, ALPHA-HELIX, BH3, MIMICRY
Exp. method : X-RAY DIFFRACTION ( 1.54 Å )
Citation :

Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.

Boersma, M.D.,Haase, H.S.,Peterson-Kaufman, K.J.  et al.
(2012)  J.Am.Chem.Soc.  134 : 315

PubMed: 22040025
DOI: 10.1021/JA207148M

Reaction

Chain : A
UniProt : Q07817 (B2CL1_HUMAN)
Reaction : -