Brand  (β version)

PDB ID: 465D

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9AD 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamide PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 465D   PDBj   RCSB PDB   PDBe
Header : DNA
Title : STRUCTURE OF THE TOPOISOMERASE II POISON BOUND TO DNA
Release Data : 1999-08-25
Compound :
mol_id molecule chains
1 DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') A
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Adams, A., Guss, J.M., Collyer, C.A., Denny, W.A., Wakelin, L.P.
Keywords : TOPOISOMERASE II POISON, HEXANUCLEOTIDE, D(CGTACG)2, 9-AMINO-DACA, DNA
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2.

Adams, A.,Guss, J.M.,Collyer, C.A.  et al.
(1999)  Biochemistry  38 : 9221 - 9233

PubMed: 10413496
DOI: 10.1021/bi990352m