Brand  (β version)

PDB ID: 3ZJ7

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
C1K (1r,2s,3s,4r,5r)-4-(cyclohexylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 3ZJ7   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of strictosidine glucosidase in complex with inhibitor-1
Release Data : 2014-02-05
Compound :
mol_id molecule chains
1 STRICTOSIDINE-O-BETA-D-GLUCOSIDASE A,B
ec: 3.2.1.105
Source :
mol_id organism_scientific organism_common expression_system
1 RAUVOLFIA SERPENTINA  (taxid:4060) SERPENTWOOD ESCHERICHIA COLI M15  (taxid:1007065)
expression_system_vector_type: PLASMID
expression_system_plasmid: PQE-2
Authors : Xia, L., Lin, H., Panjikar, S., Ruppert, M., Castiglia, A., Rajendran, C., Wang, M., Schuebel, H., Warzecha, H., Jaeger, V., Stoeckigt, J.
Keywords : HYDROLASE, ALKALOID, INHIBITOR, AJMALINE
Exp. method : X-RAY DIFFRACTION ( 2.50 Å )
Citation :

Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.

Xia, L.,Lin, H.,Staniek, A.  et al.
(2015)  J.Enzyme.Inhib.Med.Chem.  30 : 472

PubMed: 25140865
DOI: 10.3109/14756366.2014.949252

Reaction

Chain : A, B
UniProt : Q8GU20 (SG1_RAUSE)
Reaction: EC: Evidence:
Physiological Direction:
3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone 3.2.1.105 PubMed:17890378
-