PDB ID: 3ZHZ
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Structure summary
Code : | 3ZHZ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue | ||||||||||||
Release Data : | 2013-10-09 | ||||||||||||
Compound : |
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Source : |
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Authors : | Bjorkelid, C., Jansson, A.M., Bergfors, T., Unge, T., Mowbray, S.L., Jones, T.A. | ||||||||||||
Keywords : | OXIDOREDUCTASE, RV2870C, DOXP/MEP PATHWAY ISPC | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.25 Å ) | ||||||||||||
Citation : |
Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
Jansson, A.M.,Wieckowska, A.,Bjorkelid, C.
et al.
PubMed: 23819803 The 1.9 A Resolution Structure of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, a Potential Drug Target.
Henriksson, L.M.,Bjorkelid, C.,Mowbray, S.L.
et al.
PubMed: 16790937 Structures of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose- 5-Phosphate Reductoisomerase Provide New Insights Into Catalysis.
Henriksson, L.M.,Unge, T.,Carlsson, J.
et al.
PubMed: 17491006 Design, Synthesis, and X-Ray Crystallographic Studies of Alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase.
Andaloussi, M.,Henriksson, L.M.,Wieckowska, A.
et al.
PubMed: 21678907 Structural Studies on Mycobacterium Tuberculosis Dxr in Complex with the Antibiotic Fr-900098.
Bjorkelid, C.,Bergfors, T.,Unge, T.
et al.
PubMed: 22281742 |
Reaction
Chain : | A, B |
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UniProt : | P64012 |
Reaction : | - |