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Ligands
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FUU 2-(3-((3-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)ureido)methyl)phenoxy)acetic acid
Non-standard Residues
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Glycosylation
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Code : 3VNG   PDBj   RCSB PDB   PDBe
Header : PROTEIN BINDING
Title : Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization
Release Data : 2013-01-16
Compound :
mol_id molecule chains synonym
1 Kelch-like ECH-associated protein 1 A Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19
fragment: UNP residues 321-609
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: KEAP1, INRF2, KIAA0132, KLHL19
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pTA2
Authors : Kunishima, N., Tanaka, T., Satoh, M., Saburi, H.
Keywords : PROTEIN-SMALL MOLECULAR COMPLEX, Beta-Propeller, Kelch Repeat Motif, Soaking, Stress Sensor, Small Molecular Binding, PROTEIN BINDING
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization

Kunishima, N.,Tanaka, T.,Satoh, M.  et al.
To be Published 

Chain : A
UniProt : Q14145 (KEAP1_HUMAN)
Reaction : -