Brand  (β version)

PDB ID: 3V07

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Ligands
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Non-standard Residues
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F6H 3,7-anhydro-1,5,6-trideoxy-5-fluoro-6-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-2-O-phosphono-D-glycero-L-allo-heptitol
Glycosylation
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Structure summary

Code : 3V07   PDBj   RCSB PDB   PDBe
Header : DNA
Title : Crystal structure of R-6'-Me-3'-fluoro hexitol nucleic acid
Release Data : 2012-02-08
Compound :
mol_id molecule chains
1 DNA (5'-D(*GP*CP*GP*TP*AP*(F6H)P*AP*CP*GP*C)-3') A,B
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Pallan, P.S., Egli, M.
Keywords : A-form DNA, 3'-fluoro hexitol nucleic acid, FHNA, R-6'-Me-FHNA, antisense oligonucleotides, DNA
Exp. method : X-RAY DIFFRACTION ( 1.24 Å )
Citation :

Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.

Pallan, P.S.,Yu, J.,Allerson, C.R.  et al.
(2012)  Biochemistry  51 : 7 - 9

PubMed: 22229409
DOI: 10.1021/bi201810r