PDB ID: 3UW4
Hetero Atom Contents
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Structure summary
Code : | 3UW4 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | Apoptosis Inhibitor | ||||||||||||||||||||||||
Title : | Crystal structure of cIAP1 BIR3 bound to GDC0152 | ||||||||||||||||||||||||
Release Data : | 2012-02-22 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Maurer, B., Hymowitz, S. | ||||||||||||||||||||||||
Keywords : | Apoptosis Inhibitor, BIR domain | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.79 Å ) | ||||||||||||||||||||||||
Citation : |
Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
Flygare, J.A.,Beresini, M.,Budha, N.
et al.
PubMed: 22413863 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q13490 (BIRC2_HUMAN) | ||||||||
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Chain : | A | ||||||||
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UniProt : | P98170 (XIAP_HUMAN) | ||||||||
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