PDB ID: 3UR4
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0BW | Methyl 3-[(3-methoxybenzoyl)amino]-4-(4-methylpiperazin-1-yl)benzoate | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
UNX | Unknown atom or ion | PoSSuM |
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Download interaction data: 3UR4
Structure summary
Code : | 3UR4 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSCRIPTION/INHIBITOR | ||||||||||||
Title : | Crystal structure of human WD repeat domain 5 with compound | ||||||||||||
Release Data : | 2011-12-14 | ||||||||||||
Compound : |
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Source : |
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Authors : | Dong, A., Dombrovski, L., Senisterra, G., Wernimont, A., Wasney, G.A., Allali Hassani, A., Nguyen, K.T., Smil, D., Bolshan, Y., Hajian, T., Poda, G., Chau, I., Al-Awar, R., Bountra, C., Weigelt, J., Edwards, A.M., Arrowsmith, C.H., Brown, P., Schapira, M., Vedadi, M., Wu, H., Structural Genomics Consortium (SGC) | ||||||||||||
Keywords : | Structural Genomics, Structural Genomics Consortium, SGC, TRANSCRIPTION, WD REPEAT DOMAIN 5, WDR5, TRANSCRIPTION-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Senisterra, G.,Wu, H.,Allali-Hassani, A.
et al.
PubMed: 22989411 |
Reaction
Chain : | A, B |
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UniProt : | P61964 (WDR5_HUMAN) |
Reaction : | - |