Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FHF N-((2r,4s)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide
ZN Zinc ion
Modified Residues
Code Name Link
CSD 3-sulfinoalanine
Code : 3U7M
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Release Data : 2012-06-27
Compound :
mol_id molecule chains synonym
1 Peptide deformylase A PDF, Polypeptide deformylase
ec: 3.5.1.88
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus  (taxid:93062) Escherichia coli  (taxid:562)
strain: COL
gene: sacol1100
expression_system_strain: C41(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET-21a(+)
Authors : Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Keywords : PDF-INHIBITOR, PDF, PEPTIDE DEFORMYLASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Lee, S.J.,Lee, S.-J.,Lee, S.K.  et al.
(2012)  Acta Crystallogr.,Sect.D  68 : 784 - 793

PubMed: 22751663
DOI: 10.1107/S0907444912011912

Chain : A
UniProt : Q5HGZ3 (DEF_STAAC)
Reaction : Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.