PDB ID: 3TU7
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Structure summary
Code : | 3TU7 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||||||||||||||
Title : | Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-L-prolinamide (BMS-189664) | ||||||||||||||||||||||||||||||||||||
Release Data : | 2011-10-12 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Malley, M., Sack, J.S. | ||||||||||||||||||||||||||||||||||||
Keywords : | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.49 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Molecular design and structure-activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Das, J.,Kimball, S.D.,Hall, S.E.
et al.
PubMed: 11738570 |
Reaction
Chain : | H | ||||||||
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UniProt : | P00734 (THRB_HUMAN) | ||||||||
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Chain : | I |
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UniProt : | P09945 (HIRV2_HIRME) |
Reaction : | - |