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Ligands
Code Name Style Show Link
JRO 6,7,9-trihydroxy-3-methyl-1h-benzo[G]isochromen-1-one
GOL Glycerol
Non-standard Residues
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Glycosylation
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Code : 3TL1   PDBj   RCSB PDB   PDBe
Header : BIOSYNTHETIC PROTEIN
Title : Crystal structure of the Streptomyces coelicolor WhiE ORFVI polyketide aromatase/cyclase
Release Data : 2012-04-04
Compound :
mol_id molecule chains synonym
1 Polyketide cyclase A,B WhiE ORF VI
Source :
mol_id organism_scientific expression_system
1 Streptomyces coelicolor  (taxid:1902) Escherichia coli  (taxid:469008)
gene: SCO5315, SC6G9.18
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28
Authors : Lee, M.-Y., Ames, B.D., Zhang, W., Tang, Y., Tsai, S.-C.
Keywords : Helix-grip fold, polyketide C9-C14 aromatase/cyclase, linear poly-beta-ketone intermediate, BIOSYNTHETIC PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Insight into the Molecular Basis of Aromatic Polyketide Cyclization: Crystal Structure and in Vitro Characterization of WhiE-ORFVI.

Lee, M.Y.,Ames, B.D.,Tsai, S.C.
(2012)  Biochemistry  51 : 3079 - 3091

PubMed: 22432862
DOI: 10.1021/bi201705q

Chain : A, B
UniProt : P23154 (CYPC_STRCO)
Reaction : -