PDB ID: 3THS
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Structure summary
Code : | 3THS PDBj RCSB PDB PDBe | ||||||||||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||||||||||
Title : | Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate pentaglutamate | ||||||||||||||||||||
Release Data : | 2011-11-16 | ||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Luka, Z., Pakhomova, S., Loukachevitch, L.V., Newcomer, M.E., Wagner, C. | ||||||||||||||||||||
Keywords : | Glycine N-methyltransferase, GNMT, Folate, Folate binding, Transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||||||||||
Citation : |
Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Luka, Z.,Pakhomova, S.,Loukachevitch, L.V.
et al.
PubMed: 22037183 |
Reaction
Chain : | A, B, C, D | |||||||||
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UniProt : | P13255 (GNMT_RAT) | |||||||||
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