Het-PDB Navi2 (PDB: 3SMK)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CW7	Cotylenin a				PoSSuM
MG	Magnesium ion				PoSSuM

Non-standard Residues
Code	Name	Show
SEP	Phosphoserine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3SMK

Code :

3SMK PDBj RCSB PDB PDBe

Header :

PEPTIDE BINDING PROTEIN

Title :

Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A

Release Data :

2012-07-11

Compound :

mol_id	molecule	chains	synonym
1	14-3-3 protein sigma	A	Epithelial cell marker protein 1, Stratifin
	mutation: C38V N166H

mol_id	molecule	chains
2	TASK-3 peptide	P

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: HME1, SFN expression_system_strain: Rosetta DE3 expression_system_vector_type: Plasmid expression_system_plasmid: pPROEX HTB

mol_id	organism_scientific
2	Homo sapiens (taxid:9606)
	synthetic: yes other_details: This sequence occurs naturally in humans.

Authors :

Anders, C., Schumacher, B., Ottmann, C.

Keywords :

Helical protein, Phosphoprotein, Adapter protein, Peptide binding protein

Exp. method :

X-RAY DIFFRACTION ( 2.10 Å )

Citation :

A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.

Anders, C.,Higuchi, Y.,Koschinsky, K. et al.
(2013) Chem. Biol. 20 : 583 - 593

PDB ID: 3SMK