PDB ID: 3SL5
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ZN | Zinc ion | PoSSuM | |||
J25 | Diethyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-C]pyridine-3,6(5h)-dicarboxylate | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM |
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Download interaction data: 3SL5
Structure summary
Code : | 3SL5 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Hydrolase/Hydrolase Inhibitor | ||||||||||||
Title : | Crystal structure of the catalytic domain of PDE4D2 complexed with compound 10d | ||||||||||||
Release Data : | 2011-10-26 | ||||||||||||
Compound : |
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Authors : | Feil, S.F. | ||||||||||||
Keywords : | catalytic mechanism, cAMP hydrolysis, Hydrolase-Hydrolase Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.650 Å ) | ||||||||||||
Citation : |
Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Nankervis, J.L.,Feil, S.C.,Hancock, N.C.
et al.
PubMed: 22030030 |
Reaction
Chain : | A, B, C, D | ||||||||
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UniProt : | Q08499 (PDE4D_HUMAN) | ||||||||
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